Objective
To support research to understand and mitigate the impact of climate change on health, while recognizing the interconnection between human, animal and environmental health.
Disease focus
Climate-sensitive and vector-borne diseases such as dengue, Zika, Chikungunya, yellow fever, meningitis and cholera.

Key activities
Current Master’s of Public Health students at Senegal’s Université Cheikh Anta Diop, supported by TDR, at an implementation research workshop earlier this year.
Credit: Université Cheikh Anta Diop
RTCs trained
more than
individuals online
individuals in-person
Vector-borne diseases (VBDs) such as dengue, yellow fever and Rift Valley fever have long troubled Africa, with outbreaks becoming more frequent due to climate change. TDR is supporting research led by the Institut Pasteur de Dakar (IPD) in Senegal and the Nigerian Institute of Medical Research (NIMR) to enhance the surveillance and control of VBDs using a One Health approach, which integrates human, animal and environmental health.
Mosquitoes resting indoors and outdoors
Larvae and pupae sampling in water storage or discarded containers
Egg collection using egg-laying traps
Host-seeking mosquito collection
Credit: TDR/A. Gildas Yahouedo
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Suggested citation. TDR annual report 2024: building local research solutions to improve global health. Geneva: World Health Organization; 2025. Licence: CC BY-NC-SA 3.0 IGO.
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Cover page photo. ©
Cover caption: Angel Michael (centre) delivers her child’s urine and stool sample to Ngw’ashi Dotto Haga (left), a community health care worker, as part of the baseline parasitological assessment study.
Credit: UNDP/Kumi Media
Vector-borne diseases (VBDs) such as dengue, yellow fever and Rift Valley fever have long troubled Africa, with outbreaks becoming more frequent due to climate change. TDR is supporting research led by the Institut Pasteur de Dakar (IPD) in Senegal and the Nigerian Institute of Medical Research (NIMR) to enhance the surveillance and control of VBDs using a One Health approach, which integrates human, animal and environmental health.
This study aims to determine the effects of climate change on VBD emergence, outbreaks and spread in Senegal and Nigeria. Researchers are using virological, entomological, meteorological and vector-borne surveillance data to develop a strategic process for prevention, preparedness and mitigation responses to climate-linked VBD threats.
In Senegal, a study has found that northern and central regions have the highest dengue risk levels across 14 regions, underscoring the impact of climate change on dengue risk. A second study is evaluating the transmission of malaria, meningitis, dengue and Rift Valley fever. The goal is to enhance institutional capacity for integrating climate-related risks into public health strategies.
In Nigeria, 44.2% of individuals in a study in Oyo State tested positive for dengue virus antibodies, even though the virus was not detected in RNA samples from patients with fever. The findings suggest the need for better diagnosis of dengue as well as improved surveillance capacities.
Read about other related research projects in Kenya, Rwanda, South Africa, Uganda and United Republic of Tanzania here.